Table 3.

Change from baseline for outcomes of social functioning

		Oxytocin			Placebo
Outcome Variablea	Time Point (wks)	N	LS Mean (SE)	P-Valueb Diff>0	N	LS Mean (SE)	P-Valueb Diff>0	P-Valuec Trt Diff
SLOF-I IR	12	17	0.64 (1.19)	0.297	12	0.85 (1.42)	0.275	0.455
SLOF-P IR	12	26	−0.83 (0.96)	0.195	27	−2.61 (0.94)	0.003	0.096
SLOF-I SA	12	17	0.38 (0.32)	0.116	13	0.43 (0.36)	0.122	0.463
SLOF-P SA	12	26	0.84 (0.51)	0.050	28	0.44 (0.49)	0.188	0.287
SSPA Verbal SS	6	26	−0.09 (0.06)	0.145	28	0.16 (0.06)	0.008	0.005
	12	23	0.03 (0.07)	0.692	24	0.08 (0.07)	0.277	0.631
SSPA Nonverbal SS	6	26	−0.00 (0.07)	0.967	28	0.07 (0.07)	0.316	0.472
	12	23	0.01 (0.06)	0.878	24	0.04 (0.06)	0.537	0.748
SSPA Global SS	6	26	−0.27 (0.10)	0.007	28	0.01 (0.09)	0.950	0.045
	12	23	−0.14 (0.10)	0.152	24	−0.12 (0.10)	0.233	0.847

Abbreviations: LS, least squares; SLOF-I, Specific Levels of Functioning Scale - Informant; SLOF-P, SLOF-Participant; IR, Interpersonal Relationships; SA, Social Acceptability; SSPA, Social Skills Performance Assessment; SS, Social Skill

^aModels adjusted for baseline value and age in addition to treatment group.

^bTest for within-group change

^cTest for between-group change