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. Author manuscript; available in PMC: 2018 Jul 1.
Published in final edited form as: Am J Med. 2017 Jan 13;130(7):809–818. doi: 10.1016/j.amjmed.2016.11.045

Table 3.

Association between Various PAP therapies and Hospitalizations with Matched Medication only (control) Groups

Any
Hospitalization*
COPD-Related
Hospitalization*

N OR (95% CI), p N OR (95% CI), p

BILEVEL-PAP 298,792 298,792
  Treatment Group 9,156 0.40 (0.37, 0.43), <0.001 9,156 0.45 (0.38, 0.52), <0.001
  Medication only
(control) Group
289,636 0.47 (0.46, 0.48), <0.001 289,636 0.39 (0.38, 0.40), <0.001

CPAP 504,069 504,069
  Treatment Group 39,385 0.67 (0.65, 0.70), <0.001 39,385 0.52 (0.47, 0.59), <0.001
  Medication only
(control) Group
464,684 0.51 (0.51, 0.52), <0.001 464,684 0.36 (0.35, 0.37), <0.001

NIPPV 80,952 80,952
  Treatment Group 315 0.21 (0.15, 0.30), <0.001 315 0.29 (0.18, 0.47), <0.001
  Medication only
(control) Group
80,637 0.59 (0.58, 0.60), <0.001 80,637 0.58 (0.56, 0.60), <0.001
*

Adjusted for the propensity score, age, sex, region, insurance type, acute respiratory failure, Alzheimer’s and related dementia, anxiety or bipolar disorder, asthma, atrial fibrillation, chronic kidney disease, coronary heart disease, congestive heart failure, depression, diabetes, hypercholesterolemia or hyperlipidemia, hypertension, hypoxemia, insomnia, ischemic heart disease, lung cancer, morbid obesity, osteoarthritis, osteoporosis or rheumatoid arthritis and related disease, schizophrenia and other psychotic disorders, stroke, SABA or LABA, SAMA or LAMA, SABA+ACS, methylxanthines, ICS, ICS+LABA, oral prednisone, smoking cessation, and oxygen