Table 3.
Association between Various PAP therapies and Hospitalizations with Matched Medication only (control) Groups
Any Hospitalization* |
COPD-Related Hospitalization* |
|||
---|---|---|---|---|
N | OR (95% CI), p | N | OR (95% CI), p | |
BILEVEL-PAP | 298,792 | 298,792 | ||
Treatment Group | 9,156 | 0.40 (0.37, 0.43), <0.001 | 9,156 | 0.45 (0.38, 0.52), <0.001 |
Medication only (control) Group |
289,636 | 0.47 (0.46, 0.48), <0.001 | 289,636 | 0.39 (0.38, 0.40), <0.001 |
CPAP | 504,069 | 504,069 | ||
Treatment Group | 39,385 | 0.67 (0.65, 0.70), <0.001 | 39,385 | 0.52 (0.47, 0.59), <0.001 |
Medication only (control) Group |
464,684 | 0.51 (0.51, 0.52), <0.001 | 464,684 | 0.36 (0.35, 0.37), <0.001 |
NIPPV | 80,952 | 80,952 | ||
Treatment Group | 315 | 0.21 (0.15, 0.30), <0.001 | 315 | 0.29 (0.18, 0.47), <0.001 |
Medication only (control) Group |
80,637 | 0.59 (0.58, 0.60), <0.001 | 80,637 | 0.58 (0.56, 0.60), <0.001 |
Adjusted for the propensity score, age, sex, region, insurance type, acute respiratory failure, Alzheimer’s and related dementia, anxiety or bipolar disorder, asthma, atrial fibrillation, chronic kidney disease, coronary heart disease, congestive heart failure, depression, diabetes, hypercholesterolemia or hyperlipidemia, hypertension, hypoxemia, insomnia, ischemic heart disease, lung cancer, morbid obesity, osteoarthritis, osteoporosis or rheumatoid arthritis and related disease, schizophrenia and other psychotic disorders, stroke, SABA or LABA, SAMA or LAMA, SABA+ACS, methylxanthines, ICS, ICS+LABA, oral prednisone, smoking cessation, and oxygen