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. Author manuscript; available in PMC: 2018 Jul 1.
Published in final edited form as: Trends Microbiol. 2017 Feb 16;25(7):532–545. doi: 10.1016/j.tim.2017.01.005

Figure 3. Hypothetical Model for T6SS Deletion and MDR Maintenance in Clinical Isolates of A. baumannii.

Figure 3

The genome sequences of several MDR A. baumannii clinical isolates has shown they lack a full T6SS cluster. This model proposes that pressure to maintain drug resistance by antibiotic treatment may select for strains that either repress their T6SS or degrade the T6SS cluster, permanently inactivating the secretion system in favour of antibiotic resistance.