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. Author manuscript; available in PMC: 2018 Jul 1.
Published in final edited form as: Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2017 Feb 3;9(4):10.1002/wnan.1449. doi: 10.1002/wnan.1449

FIGURE 1.

FIGURE 1

(a) In photothermal therapy, systemically-delivered nanoparticles accumulate within solid tumors via the enhanced permeability and retention effect, which exploits the leaky tumor vasculature. Once within the tumor, near-infrared light is applied to cause the nanoparticles to generate heat to kill the surrounding tumor tissue. (b) Four of the most commonly employed AuNPs for photothermal therapy include silica core/ gold shell nanoshells, gold nanorods, hollow gold nanocages, and nanostars. (Nanorod, nanocage, and nanostar images reprinted with permission from Ref 10. Copyright 2011 Wiley, Ref 11. Copyright 2007 Wiley-VCH Verlag GmbH & Co. KGaA, and Ref 12. Copyright 2015 Elsevier)