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. Author manuscript; available in PMC: 2018 Jul 1.
Published in final edited form as: Pain. 2017 Jul;158(7):1241–1253. doi: 10.1097/j.pain.0000000000000905

Table 1.

Neuropathic pain induced changes in ventrolateral periaqueductal gray on (vlPAGon) neurons.

Pre-paclitaxel Post-paclitaxel Pre-vehicle Post-vehicle

Stim Mean Freq (Hz) No of neurons Mean Freq (Hz) No of neurons P value No of rats Mean Freq (Hz) No of neurons Mean Freq (Hz) No of neurons P value No of rats
Spont 6.6 ± 0.28 52 18.8±0.1 38 <0.01 14 6.8±0.9 64 6.1±1.6 64 >0.05 14

Pre 7.4±1.6 52 20.3±2.1 38 <0.01 14 5.1±1.3 64 8.1±2.2 64 >0.05 14
38° 12.2±2.4 52 24.4±2.8 38 <0.05 14 9.8±2.1 64 11.1±2.8 64 >0.05 14
Post 6.2±1.5 52 19.8±1.7 38 <0.01 14 7.8±1.5 64 7.1±1.7 64 >0.05 14

Pre 5.90±1.1 52 19.8±1.3 38 <0.01 14 6.4±1.8 64 9.1±1.9 64 >0.05 14
42° 10.86±1.8 52 25.1±2.6 38 <0.01 14 11.5±2.3 64 10.9±2.5 64 >0.05 14
Post 6.70±1.3 52 17.2±1.8 38 <0.05 14 7.9±1.6 64 8.5±1.8 64 >0.05 14

Pre 6.8±1.2 52 21.3±2.3 38 <0.01 14 7.5±1.8 64 7.5±2.3 64 >0.05 14
48° 19.2±2.2 52 30.6±2.7 38 <0.01 14 17.2±2.5 64 18.5±2.6 64 >0.05 14
Post 7.3±1.5 52 20.3±1.8 38 <0.01 14 8.8±1.3 64 6.5±1.9 64 >0.05 14

Pre 6.6±1.6 52 19.1±1.7 38 <0.01 14 8.1±1.5 64 7.0±1.7 64 >0.05 14
51° 24.6±2.2 52 37.2±2.7 38 <0.01 14 19.1±2.91 64 20.8±2.9 64 >0.05 14
Post 7.1±1.3 52 22.3±2.4 38 <0.01 14 7.9±1.8 64 8.5±1.5 64 >0.05 14

Freq = frequency; Spont = spontaneous; Stim = stimulation