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. Author manuscript; available in PMC: 2018 May 1.
Published in final edited form as: Cancer Res. 2017 May 1;77(9):2318–2327. doi: 10.1158/0008-5472.CAN-16-3346

Figure 3. In Vitro Characterization of Novel Granzyme B Peptide.

Figure 3

A) Chemical structure of NOTA-GZP. B) A representative plot of enzyme activity at increasing concentrations of NOTA-GZP. Each point represents the mean of 6 replicates ± SEM. A non-linear regression was fit to the points using GraphPad Prism. C) Enzyme specificity plot for radiolabeled 68Ga-NOTA-GZP. Bars represent the mean of 4 replicates ± SEM. *** P < 0.0001 by one-way ANOVA with a Bonferroni post test, comparison to granzyme B binding.