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. Author manuscript; available in PMC: 2017 Nov 1.
Published in final edited form as: Nat Genet. 2017 May 1;49(6):887–894. doi: 10.1038/ng.3857

Figure 1. Cytosine methyltransferase DIM-2 can mediate RIP.

Figure 1

a, The 802-bp tester construct contains one endogenous (“left”) and one ectopic (“right”) copy of an 802-bp region of the Neurospora genome (ref. 18). The “no-repeat” construct specifically lacks the ectopic repeat copy.

b, RIP mutation profiles of the 802-bp construct. Top row (left to right): crosses X1{24}, X2{48} and X3{48}; bottom row (left to right): crosses X4{24}, X5{24} and X6{24}. The number of mutations is reported per site per spore. Cross X1 was published previously (ref. 18).

c, RIP does not occur in the absence of the ectopic repeat copy. Cross X7{48}.

The number of spores analyzed for each cross is provided in curly brackets. Strain and cross genotypes are provided in Supplementary Table 1 and 2, respectively.