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. Author manuscript; available in PMC: 2017 Jun 18.
Published in final edited form as: Neuron. 2017 Feb 22;93(4):723–724. doi: 10.1016/j.neuron.2017.02.016

Figure 1.

Figure 1

Enkephalin Modulates the Sensing of a Strong Pain Stimulus

(A) Stimulation by pruritogens and low levels of capsaicin leads to itch and weak pain.

(B) Increased neuronal firing associated with high levels of capsaicin leads to the activation of neurons that release enkaphalin, which modulates the degree of pain.