Table 1.
Yeast Set1 | Human Set1-like Complexes | |||
---|---|---|---|---|
SET1A/B | MLL1/MLL2 | MLL3/MLL4 | ||
Enzymatic subunit | Set1 | SET1A/B | MLL1/MLL2 | MLL3/MLL4 |
Common subunits forming the WRAD subcomplex | Bre2 | ASH2L | ASH2L | ASH2L |
Swd1 | RbBP5 | RbBP5 | RbBP5 | |
Swd3 | WDR5 | WDR5 | WDR5 | |
Sdc1 | DPY30 | DPY30 | DPY30 | |
Distinct subunits | Swd2 | WDR82 | ||
Spp1 | CXXC1 | |||
Menin | PTIP & PA1 | |||
HCF1 | HCF1/2 | NCOA6 | ||
UTX |