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Yeast Set1 & human Set1-like complexes methylate histone H3K4
| Yeast Set1 | Human Set1-like Complexes | |||
|---|---|---|---|---|
| SET1A/B | MLL1/MLL2 | MLL3/MLL4 | ||
| Enzymatic subunit | Set1 | SET1A/B | MLL1/MLL2 | MLL3/MLL4 |
| Common subunits forming the WRAD subcomplex | Bre2 | ASH2L | ASH2L | ASH2L |
| Swd1 | RbBP5 | RbBP5 | RbBP5 | |
| Swd3 | WDR5 | WDR5 | WDR5 | |
| Sdc1 | DPY30 | DPY30 | DPY30 | |
| Distinct subunits | Swd2 | WDR82 | ||
| Spp1 | CXXC1 | |||
| Menin | PTIP & PA1 | |||
| HCF1 | HCF1/2 | NCOA6 | ||
| UTX | ||||
