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. Author manuscript; available in PMC: 2018 Jun 1.
Published in final edited form as: Semin Cell Dev Biol. 2017 Feb 24;66:36–42. doi: 10.1016/j.semcdb.2017.02.004

Figure 2. Summary of WNT-mediated gastric patterning mechanisms in vivo and in vitro.

Figure 2

A. WNT/β-catenin signaling promotes fundus specification from the pool of gastric progenitor cells during E9–10. B. WNT activation promotes generation of fundic human gastric organoids (hGOs), while repressing antral specification, from hPSC-derived posterior foregut spheroids.