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Summary of children's antibody responses to RSV.
| Age group | Maternal antibody | Acquired antibody responses |
||||
|---|---|---|---|---|---|---|
| NT | IgG3 | Antibody affinity maturation | Cross reactivity to G proteins | Neutralization epitope-specific IgG | ||
| 0–3 mo | ++ | ± | + | − | − | − |
| 4–6 mo | + | + | ++ | − | − | − |
| 7–12 mo | − | ++ | +++ | + | + | − |
| 13–18 mo | − | ++ | +++ | + | + | + |
| 19–36 mo | − | +++ | +++ | ++ | + | ++ |
