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. 2017 Jan 11;16:275–283. doi: 10.1016/j.ebiom.2017.01.011

Fig. 3.

Fig. 3

Experimental design and GTT in rat offspring. A: Experiment design. Circles designate females and squares designate males. Hyperandrogenism and normal female rats (HA-F0 and Ctrl-F0) were mated with normal female to generate offspring (F1). B: Testosterone and Free Androgen Index (FAI) levels in F0 ovarian follicles. C: Fasting glucose levels of 3-week-old offspring (left panel), GTT and AUC of 3-week-old offspring (middle and right panel). n = 8 and 22 for control and hyperandrogenism, respectively. D: Fasting glucose levels of 8-week-old offspring (left panel), GTT and AUC of 8-week-old offspring (middle and right panel). n = 10 and 16 for control and hyperandrogenic, respectively. E and F: Insulin levels of 3- and 8-week-old offspring in GTT. Data are presented as means ± SE. *p < 0.05, vs. Ctrl, **p < 0.01, vs. Ctrl, ***p < 0.001, vs. Ctrl.