Table 1.
Follow-up characteristics of children born to mothers without or with hyperandrogenism.
| Without hyperandrogenism | With hyperandrogenism | p-Value | |
|---|---|---|---|
| No. of subjects | 1060 | 156 | |
| Age (months) | 59.9 ± 13.1 | 60.4 ± 12.5 | NS |
| BMI (kg/m2) | 15.3 ± 1.1 | 15.6 ± 1.6 | NS |
| Blood pressure (mmHg) | |||
| Systolic blood pressure | 98.1 ± 13.9 | 98.1 ± 13.9 | NS |
| Diastolic blood pressure | 55.8 ± 10.1 | 55.7 ± 10.2 | NS |
| Blood lipids (mmol/L) | |||
| Triglyceride | 0.72 ± 0.20 | 0.71 ± 0.27 | NS |
| Cholesterol | 4.29 ± 0.70 | 4.33 ± 0.89 | NS |
| HDL | 1.49 ± 0.27 | 1.45 ± 0.24 | NS |
| LDL | 2.29 ± 0.56 | 2.41 ± 0.71 | NS |
| Fasting glucose (mmol/L) | 4.73 ± 0.43 | 4.82 ± 0.43 | < 0.05 |
| Fasting insulin (μU/mL) | 3.52 ± 1.62 | 4.13 ± 2.69 | < 0.01 |
| HOMA-IR | 0.80 ± 0.45 | 0.89 ± 0.72 | < 0.05 |
| OGTTa | |||
| Fasting glucose (mmol/L) | 4.60 ± 0.41 | 4.72 ± 0.37 | < 0.05 |
| 60 min glucose (mmol/L) | 6.08 ± 0.81 | 6.05 ± 0.42 | NS |
| 120 min glucose (mmol/L) | 4.85 ± 0.70 | 5.13 ± 0.73 | < 0.05 |
| Fasting insulin (μU/mL) | 3.12 ± 1.88 | 3.58 ± 1.62 | < 0.05 |
| 60 min insulin (μU/mL) | 13.51 ± 7.38 | 15.76 ± 8.67 | NS |
| 120 min insulin (μU/mL) | 4.72 ± 4.09 | 10.53 ± 5.25 | < 0.01 |
Data = mean ± SD, P values were calculated by t-test.
a
n = 132 and 80 for singleton born to mother without and with hyperandrogenism, respectively.