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Diagram summarizing the role of MyoD in brown adipocyte and myoblast fate determination. Loss of MyoD stimulates transdifferentiation of myoblasts into brown adipocytes. Conversely, overexpression of MyoD inhibits brown adipogenesis through myogenic transdifferentiation of brown adipocytes and miR-133-mediated mRNA decay of Prdm16 and Igf1r.
