Table 3. Histopathologic characteristics of patients with advanced pancreatic cancer.
| Characteristics | Previously explored (n=50) | R2-resection (n=101) | P value |
|---|---|---|---|
| pT stage, n (%) | <0.001† | ||
| T0 | 0 (0) | 0 (0) | |
| T1 | 11 (22.0) | 3 (3.0) | |
| T2 | 5 (10.0) | 8 (8.0) | |
| T3 | 32 (64.0) | 78 (77.2) | |
| T4 | 2 (4.0) | 12 (11.9) | |
| pN stage, n (%) | <0.001 | ||
| N0 | 26 (52.0) | 19 (18.8) | |
| N1 | 24 (48.0) | 82 (81.2) | |
| Tumor size, median (IQR) cm | 2.5 (1.5–3.5) | 3 (2.5–4.0) | 0.064 |
| Vascular invasion, n (%) | 23 (46.0) | 54 (53.5) | 0.388 |
| Perineural invasion, n (%) | 32 (64.0) | 87 (86.1) | 0.002 |
| Positive nodes (n), median (IQR) | 0 (0–2.3) | 3 (1.0–6.0) | 0.001 |
| Total nodes (n), median (IQR) | 16 (13.0–20.0) | 16 (12.0–22.0) | 0.432 |
| Overall survival A, median†† (months) | 19 | 10 | <0.001 |
| Overall survival B, median§ (months) | 25 | 10 | <0.001 |
†, statistical analysis performed on T0–T2 vs. T3–T4 tumors; ††, overall survival A was calculated from the time of current pancreatectomy to death; §, overall survival B was calculated from the time of the initial exploration to death. IQR, interquartile range.