Fig. 3.

Mutational patterns of B-cell function genes in diffuse large B-cell lymphoma (DLBCL).

A: Schematic location of B-cell function gene mutations, and sequence alignment of protein across distinct species. B: Circos diagram of the correlation between genes, representing the combinations of mutations in different genes. C: Distribution of gene mutations in patients with germinal center B-cell (GCB)/non-GCB subtype and patients with and without double BCL-2/MYC expression. D: Distribution of NF-κB activation in patients with and without B-cell function gene mutations.