Table 5.

Multivariate analysis results for patients undergoing umbilical cord blood transplantation for MDS between 2004 and 2013, with the CIBMTR MDS Transplantation Score as the main effect

Relapse
			95% CI	95% CI		Overall
CIBMTR MDS score	N	RR	Lower Limit	Upper Limit	p-value	p-value
Low	19	1				0.3072
Intermediate	83	0.749	0.281	1.997	0.5631
High/Very high	44	0.869	0.304	2.486	0.7932
Missing	34	1.378	0.499	3.805	0.5366
Conditioning regimen
Myeloablative	62	1				0.0008
RIC/NMA	118	3.963	1.775	8.85	0.0008
TRM
			95% CI	95% CI		Overall
CIBMTR MDS score [23]	N	RR	Lower Limit	Upper Limit	p-value	p-value
Low	19	1				0.7711
Intermediate	83	0.752	0.32	1.768	0.5131
High/Very high	44	1.044	0.463	2.352	0.9177
Missing	34	0.802	0.318	2.02	0.6397
HCT-CI
0	58	1				0.0225
1–2	50	1.085	0.611	1.928	0.781
≥3	61	2.132	1.249	3.638	0.0055
Missing	11	0.963	0.418	2.22	0.9301
DFS
			95% CI	95% CI		Overall
CIBMTR MDS score	N	RR	Lower Limit	Upper Limit	p-value	p-value
Low	19	1				0.3668
Intermediate	83	0.845	0.401	1.782	0.6591
High/Very high	44	1.058	0.535	2.092	0.8706
Missing	34	1.212	0.595	2.468	0.5968
HCT-CI
0	58	1				0.0308
1–2	50	1.093	0.64	1.865	0.7454
≥3	61	1.877	1.115	3.161	0.0178
Missing	11	1.336	0.809	2.206	0.2575
OS
			95% CI	95% CI		Overall
CIBMTR MDS score	N	RR	Lower Limit	Upper Limit	p-value	p-value
Low	20	1				0.6573
Intermediate	85	0.81	0.377	1.738	0.5881
High/Very high	44	1.062	0.507	2.227	0.8726
Missing	34	0.939	0.467	1.886	0.8589
HCT-CI
0	60	1				0.0016
1–2	50	1.064	0.591	1.915	0.8364
≥3	61	2.084	1.228	3.537	0.0065
Missing	12	1.738	1.056	2.86	0.0295