Table 8.

Medications for headaches.

Medication	Usual adolescent dose	Comments
Supplements
Riboflavin	200 mg bid or 400 mg daily	Available as a single supplement or in combination with others (e.g., MigreLief)
Co-enzyme Q10	300 mg daily in 2–3 divided doses
Magnesium	250 mg daily
Antihistamines
Pizotifen	1–1.5 mg nightly	Helpful for co-morbid insomnia and for poor appetite. Can cause weight gain. Pizotifen is not available in all countries
Cyproheptadine	2–8 mg nightly
Tricyclics
Amitriptyline	10–25 mg nightly (Up to 50 mg may be tolerated)	Useful for co-morbid fibromyalgia and abdominal hyperalgesia. Can cause lightheadedness and fatigue even at low doses. Can take 4 weeks to become effective.