Food Consumption. (a) kcals per week with EtOH males, (b) kcals with EtOH females, (c) kcals per week without EtOH males, and (d) kcals without EtOH females. Diet significantly affected both total kcals per week (food plus ethanol) and kcals without ethanol (food only), as HFD and RC mice exhibited increased kcals than TEN (except Week 14, where HFD was greater than the other groups). For many weeks during the experiment, food consumption was reduced in female mice compared to males. Lastly, weeks 13, 15, 17–18, mice consuming both HFD and ethanol consumed more kcals than RC ethanol, but HFD water and RC water were equal. Ethanol consumption reduced food intake in both sexes. Open circles indicate water, and filled circles indicate alcohol. (M) and (F) refer to male and female graphs, respectively. ^ significant diet x drink interaction, @ indicates ethanol difference, † significant diet difference, ‡ significant sex difference at p < .05