Table 2.

Regions showing ALFF value differences between patients with leukoaraiosis and control subjects

Brain regions	Number of cluster voxels	MNI coordinate (mm)			Maximum t
		x	y	z
Decreased ALFF
Left PHG	40	−30	−45	−9	−3.86
Increased ALFF
Left ISLL	53	−24	−75	−45	3.80
Right SOFG	41	22	6	−6	4.39

Comparisons were performed at p < .01 and corrected for multiple comparisons using the AlphaSim program. x, y, and z are coordinates of peak locations in the MNI space. Maximum t shows ALFF differences between the leukoaraiosis group and healthy subjects. A positive maximum t‐score represents an increase, and a negative maximum t‐score represents a decrease. ALFF, amplitude of low‐frequency fluctuations; MNI, Montreal Neurological Institute Coordinate System or Template; PHG, parahippocampal; ISLL, inferior semi‐lunar lobule; SOFG, frontal superior orbital gyrus.