Skip to main content
. Author manuscript; available in PMC: 2017 Jun 19.
Published in final edited form as: J Mol Biol. 2016 Sep 3;428(20):3903–3910. doi: 10.1016/j.jmb.2016.08.026

Figure 2.

Figure 2

The cysteine mutations stabilize truncated EC+TM FGFR dimers in the absence of ligands. Solid magenta circles: C178R FGFR1; Solid blue diamonds: C342R FGFR2; Solid red squares: C228R FGFR3. Top panels: FRET efficiencies for the mutants (solid color symbols) and the wild-types (open black symbols,8). Middle panels: Donor concentration versus acceptor concentration in each vesicle. Bottom panels: Dimeric fraction as a function of total receptor concentration (donors+acceptors). The QI-FRET method, used for data collection and analysis, has been described in detail in refs. 34,35,50