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. 2017 Jun 11;112(11):2419–2427. doi: 10.1016/j.bpj.2017.05.001

Figure 3.

Figure 3

Blocking cell division impairs CAM within tissues. (a) Treatment with mitomycin C abolishes cell divisions over a 14 hr period of observation. (b) Untreated tissues exhibit greater CAM compared to (c) tissues treated with mitomycin C. (d) The fraction of tissues exhibiting at least one period of CAM is significantly reduced in tissues treated with mitomycin C, as compared to untreated tissues. (e) The fraction of rotating tissues that exhibit switches in the direction of CAM is significantly reduced in tissues treated with mitomycin C, as compared to untreated tissues. To generate these plots, rotational motion starting 90 minutes after the beginning of experimental observation was analyzed to ensure that cell division did not immediately precede the period of analysis. p < 0.05. To see this figure in color, go online.