Figure 5.

Simulations and experiments suggest that the location of cell division influences the onset of CAM. (a) To evaluate whether the position of a dividing cell within the tissue might contribute to the onset of CAM, all divisions were binned by radial position. In both (b) simulations and (c) experiments, divisions at the periphery of the tissue more frequently precede a period of CAM than divisions closer to the tissue center. (d) Similarly, cell divisions were binned by the angle along which the cell divides to determine whether this property might contribute to CAM. In this case, (e) simulations and (f) experiments both reveal that the orientation of the division axis does not preferentially promote CAM. ^∗p < 0.05. To see this figure in color, go online.