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. 2017 Jun 14;61(1):1331658. doi: 10.1080/16546628.2017.1331658

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© 2017 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 6. — In vitro inhibiting effects of CTMS and CCMS on oleic acid-induced lipid accumulation in HepG2 cells. (a) The MTT assay results (x ± s, n = 6); (b) Oil red O staining maps of HepG2 cells; (c) Lipid accumulation inhibiting results; (d): Inhibiting effects on the TG content.

Note: Vehicle: stained with only high glucose DMEMcontaining 10% FBS; Model: stained with high glucoseDMEM containing 10% FBS and 0.2mM(final concentration,same below) oleic acid; Ber (Berberine, positive):1.0 × 106 μg L−1 berberine; CTMS-H: 1.0 × 106 μg L−1715 CTMS; CTMS-M: 1.0 × 105 μg L−1 CTMS; CTMS-L:1.0 × 104 μg L−1 CTMS; CCMS-H: 1.0 × 106μg L−1CCMS; CCMS-M: 1.0 × 105μg L−1 CCMS; CCMS-L:1.0 × 104 μg L−1 CCMS. (###p < 0.001 when compared tothe control; *p < 0.05,**p < 0.01,***p < 0.001 when com-720 pared with the model).