Table 2.
Baseline characteristics of the screening trial cohort
| Control Group | Screened Group | P Value* | |
|---|---|---|---|
| No. of participants | 713 (100) | 711 (100) | |
| Age, mean (range) | 60.2 (41.5–77.7) | 59.9 (42.5–77.8) | 0.45 |
| Women | 387 (54.3) | 385 (54.2) | 0.96 |
| Active smokers | 361 (50.6) | 366 (51.5) | 0.85 |
| Never smokers | 11 (1.5) | 13 (1.8) | |
| Former smokers | 341 (47.8) | 332 (46.7) | |
| No. of pack-years: | 0.17 | ||
| <20 | 118 (16.8) | 125 (17.9) | |
| 20-40 | 323 (46.0) | 276 (39.5) | |
| 40-60 | 172 (24.5) | 193 (27.7) | |
| 60-80 | 62 (8.8) | 69 (9.9) | |
| 80+ | 27 (3.8) | 35 (5.0) | |
| Diabetes | 58 (8.1) | 61 (8.6) | 0.76 |
| Hypertension | 238 (33.4) | 217 (30.5) | 0.25 |
| CAD | 139 (19.5) | 144 (20.3) | 0.72 |
| CHF | 4 (0.6) | 14 (2.0) | 0.017 |
| CVA | 12 (1.7) | 20 (2.8) | 0.15 |
| COPD | 95 (13.3) | 122 (17.2) | 0.04 |
| Pulmonary fibrosis | 1 (0.1) | 3 (0.4) | 0.32 |
| Asthma | 65 (9.1) | 64 (9.0) | 0.94 |
| Kidney disease | 9 (1.3) | 9 (1.3) | 1.0 |
| Family history lung cancer | 182 (25.5) | 183 (25.7) | 0.93 |
| Cough/shortness of breath | 251 (35.2) | 252 (35.4) | 0.92 |
Definition of abbreviations: CAD = computer-aided detection; CHF = congestive heart failure; COPD = chronic obstructive pulmonary disease; CVA = cerebrovascular accident.
Data are presented as No. (%) unless otherwise noted.
*
P value for null hypothesis that there is no difference in the control and screened groups.