Table 1. DSS Increases Tumor Incidence in CACTg/WT;ApcΔ580/WT Mice.
Vehicle | DSS | |||||||
---|---|---|---|---|---|---|---|---|
| ||||||||
n | # Tumors | Incidence (%) | # per mousea | n | # Tumors | Incidence (%) | # per mousea | |
Any Tumor | 9 | 12 | 20.9 | 1.33±0.24 | 37 | 186 | 97.4* | 5.03±0.56# |
Cecum | 2 | 2 | 4.7 | 1.00±0.00 | 30 | 60 | 81.6* | 2.00±0.32# |
Proximal colon | 0 | 0 | 0.0 | 0.00 | 15 | 22 | 34.2* | 1.47±0.29# |
Distal colon | 8 | 10 | 18.6 | 1.25±0.25 | 28 | 104 | 73.7* | 3.71±0.35# |
Proximal + Distal | 8 | 10 | 18.6 | 1.25±0.25 | 30 | 126 | 78.9* | 4.20±0.40# |
No Tumor | 34 | 0 | 79.1 | 1 | 0 | 2.6 | ||
Total Mice | 43 | 38 |
Notes: Significantly different from the vehicle group
Chi-square test, p<0.05;
Student's T-tests, p<0.05.
Average number of tumors per tumor-bearing mouse