Table 4.
Total effect of fibromyalgia treatment (pregabalin vs placebo) on restorative sleep improvement (measured using the Sleep Quality Daily Diary score), and indirect effect via pain scale reduction
| Type of effect | Mean change in Sleep Quality score |
|---|---|
| Total effect (irrespective of whether pain reduction occurs) | |
| Pregabalin treatment → restorative sleep | −1.295 |
| Pregabalin treatment → pain reduction → restorative sleep | |
| Indirect or mediated effect (via pain reduction) | |
| Pregabalin treatment → pain reduction → restorative sleep | −0.718 |