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The methyltransferase and C-terminal domain of the HMPV L protein (PDB 4UCI) is shown, with domains colored as in Figure 2. Residues that are required for methyltransferase activity are shown in magenta with the K-D-K-E residues in a lighter shade. S-adenosyl methionine is shown in black, and GTP (which represents the RNA substrate) in grey.
