Skip to main content
. Author manuscript; available in PMC: 2017 Sep 1.
Published in final edited form as: Histol Histopathol. 2016 Dec 19;32(9):917–928. doi: 10.14670/HH-11-856

Figure 6. Vatalanib increased number of VM and novel IV formulation of HET0016 decreased VM of human GBM in rat model.

Figure 6

(A) Immunohistochemistry data showing PAS stain representing increased VM (pink vessel-like strictures due to PAS+) in Vatalanib treated tumors compared to vehicle. VM was significantly decreased in HET0016 treated groups both IP and IV compared to vehicle or Vatalanib (less number of pink vessel-like structures). Brown cells are human marker MHC-1 positive cells (human U251 GBM cells). The pink vessel-like structures are lined by brown MHC-1 positive cells.