Fig. 3.

The relative mRNA expression of MAPK1, MAPK3, SMAD2, SMAD3, BMP6, and BMP15 standardized with mRNA expression of beta-actin in oocytes (OOs) during the anestrus, estrus, and diestrus stages. Gene expression of MAPK1 and MAPK3 in OOs during the estrus cycle (a, b). Gene expression of SMAD2 and SMAD3 in OOs during the estrus cycle (c, d). Gene expression of BMP6 and BMP15 in OOs during the estrus cycle (e, f). Different superscripts (a–b) represent significant differences among groups (P < 0.05). AN OO oocytes in anestrus stage, ES OO oocytes in estrus stage, DI OO oocytes in diestrus stage