Table 5.
Clinical characteristics and IVF laboratory parameters of PCOS patients in different levels of TL
| Characteristics | TL <1 group (N = 41) | TL ≥1 group (N = 24) | P a |
|---|---|---|---|
| Age, years, mean ± SD | 30.3 ± 3.6 | 30.1 ± 5.3 | 0.834 |
| BMI, kg/m2, median (IQR) | 21.6 (20.2–23.7) | 21.6 (18.7–23.9) | 0.693 |
| Duration of infertility, y, median (IQR) | 5 (3–7) | 3 (2–4) | 0.006* |
| Basal serum FSH level, IU/L, mean ± SD | 6.9 ± 2.3 | 6.6 ± 1.4 | 0.505 |
| Basal serum LH level, IU/L, median (IQR) | 6.9 (4.3–11.9) | 5.2 (4.1–7.2) | 0.073 |
| FSH/LH, median (IQR) | 1.0 (0.6–1.5) | 1.2 (0.9–1.8) | 0.082 |
| Basal serum testosterone level, nmol/L, median (IQR) | 1.8 (1.1–2.3) | 1.8 (1.5–2.4) | 0.605 |
| Retrieved oocytes, median (IQR) | 15 (12–22) | 14 (10–17) | 0.273 |
| Metaphase II oocytes, mean ± SD | 15 ± 6 | 13 ± 5 | 0.202 |
| Proportion of mature oocytes, %, median (IQR) | 92.9 (86.2–100) | 91.3 (80.0–100) | 0.589 |
| Available embryos, mean ± SD | 10 ± 5 | 8 ± 4 | 0.206 |
| Good quality embryos, median (IQR) | 3 (1–5) | 3 (1–5) | 0.848 |
| Rate of good quality embryos, median (IQR) | 33.3 (7.8–54.4) | 33.3 (19.9–67.1) | 0.309 |
| Serum estrogen level on HCG day/retrieved oocytes, ng/L, mean ± SD | 219 ± 93 | 290 ± 144 | 0.043* |
| Serum estrogen level on HCG day/metaphase II oocytes, ng/L, mean ± SD | 245 ± 88 | 331 ± 159 | 0.024* |
| Pregnancy rate, n (%) | 18 (60.0) | 12 (57.1) | 0.838 |
| Miscarriage rate, n (%) | 0 (0) | 2 (16.7) | 0.152 |
| Cumulative pregnancy rate, n (%) | 31 (77.5) | 16 (69.6) | 0.486 |
| Cumulative rate of taking baby home, n (%) | 27 (67.5) | 13 (56.5) | 0.384 |
| Cumulative miscarriage rate, n (%) | 4 (12.9) | 3 (18.8) | 0.676 |
*P < 0.05 was considered statistically significant
a P values: t test for age, basal serum FSH level, metaphase II oocytes, available embryos, serum estrogen level on HCG day/retrieved oocytes and serum estrogen level on HCG day/metaphase II oocytes; Mann–Whitney U test for other continuous variables; chi-square or Fisher’s exact test for categorical variables