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. 2017 Jun 13;12:4415–4431. doi: 10.2147/IJN.S129989

Figure 4.

Figure 4

TEM, SEM, and AFM images of ATIQCTPC’s particles.

Notes: (A) The TEM image of ATIQCTPC in aqueous solution (pH 7, 10−7 M). (B) The SEM image of the lyophilized powders from aqueous solution of ATIQCTPC (pH 7, 10−7 M). (C) The AFM image of rat plasma alone; no particle could be seen. (D) The AFM image of NS alone, and the height of the particle is 330.3 nm. (E) ATIQCTPC in rat plasma (10−7 M), and the height of the particle is 80.6 nm. (F) Mesoscale simulation of ATIQCTPC forming a nanoparticle.

Abbreviations: TEM, transmission electron microscopy; SEM, scanning electron microscopy; AFM, atomic force microscopy; ATIQCTPC, (6S)-3-acetyl-4-oxo-N-(2-(3,4,5, 6-tetrahydroxy-tetrahydro-2H-pyran-2-carboxamido)ethyl)-4,6,7,12-tetrahydroindolo[2,3-a]quinolizine-6-carboxamide; NS, normal saline; Min, minimum.