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. 2017 Jun 19;7:3759. doi: 10.1038/s41598-017-03696-8

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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PGE₂, 6-keto-PGF_1α and LTC₄ peritoneal levels in male and female mice after zymosan-induced peritonitis. Mice were treated with zymosan (i.p.), sacrificed at the indicated time points and (A) PGE₂ and (C) LTC₄ were measured in peritoneal exudates from male and female mice, and (B) 6-keto-PGF_1α was measured in peritoneal exudates 4 hrs after zymosan injection. Time zero (T0) corresponded to untreated mice. Values represent means ± S.E.M; n = 10 mice/T0; n = 10 mice/2 hrs; n = 10 mice/4 hrs; n = 6 mice/8 hrs. ^###p < 0.001 and ^#p < 0.05, male vs female mice; two-way ANOVA plus Bonferroni (A and C) and two-tailed Student’s t test (B).