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. 2017 Jun 14;12:1731–1740. doi: 10.2147/COPD.S121723

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© 2017 Beier et al. This work is published and licensed by Dove Medical Press Limited

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Symptomatic patients: change from baseline in E-RS Total and domain symptom scores versus placebo (A) and percentage of E-RS responders (B) at week 6.

Notes: Percentage reduction is shown in brackets. Placebo N=60, aclidinium 400 μg N=116, tiotropium 18 μg N=101. *P<0.05, **P<0.01, ***P<0.001 versus placebo; ^#P<0.05 versus tiotropium. Scores: 0–40 for Total, 0–17 for Breathlessness, 0–12 for Chest Symptoms, 0–11 for Cough and Sputum.

Abbreviations: E-RS, Evaluating Respiratory Symptoms; LS, least squares; OR, odds ratio.