Table 6.
Expression of PD-L1, PD-L2, CTLA-4, PD-1, and CD8+ tumor-infiltrating lymphocytes in primary and recurrent tumors
| Patient | PD-L1 (H-score)
|
PD-L2 (H-score)
|
CTLA-4 (H-score)
|
PD-1 (H-score)
|
CD8 (H-score)
|
|||||
|---|---|---|---|---|---|---|---|---|---|---|
| Primary site | Site of recurrence | Primary site | Site of recurrence | Primary site | Site of recurrence | Primary site | Site of recurrence | Primary site | Site of recurrence | |
| A | 6.6 | 0 | 100.6 | 58.6 | 1.1 | 0 | 0.5 | 0 | 0.9 | 0 |
| B | 0 | 1.7 | 37.7 | 63.9 | 30.6 | 5.2 | 0.8 | 0.8 | 3 | 5.2 |
| C | 0 | 7.1 | 48.7 | 37.7 | 41.5 | 3 | 2.2 | 5.2 | 22.5 | 3 |
| D | 0 | 0 | 131.4 | 89.5 | 0 | 3 | 0 | 0 | 1 | 3 |
| E | 15.3 | 0 | 230.2 | 60.3 | 0 | 5.4 | 0.5 | 5 | 12.3 | 5.4 |
| F | 3 | 0 | 44.3 | 41.2 | 81.5 | 76.5 | 3.8 | 0.9 | 27.3 | 76.5 |
| G | 0 | 3.5 | 78.5 | 68.5 | 48.5 | 9.3 | 3.4 | 1.5 | 5.6 | 9.3 |
| P-value | 0.753 | 0.091 | 0.5 | 0.735 | 0.735 | |||||
Note: H-score, percentage of positive cells multiplied by intensity.
Abbreviation: H-score, Histoscore.