Table 1.
Details of dogs used for experimental procedures.
| Animal number | Age at injection (days) | Injection OD | Injection OS | In vivo data collection | Age at euthanasia (days) |
|---|---|---|---|---|---|
| 10-023 | 30 | AAV2/8mut733.CBAp.cPDE6a | None | ERG | 92 |
| VT: ob | |||||
| FI | |||||
| 11-001 | 29 | AAV2/8mut733.CBAp.cPDE6a | None | ERG | 125 |
| VT: ob | |||||
| FI | |||||
| 11-006 | 29 | AAV2/8mut733.CBAp.cPDE6a | None | ERG | 125 |
| VT: ob | |||||
| FI | |||||
| 11-007 | 29 | AAV2/8mut733.CBAp.cPDE6a | None | ERG | 125 |
| VT: ob | |||||
| FI | |||||
| 11-008 | 29 | AAV2/8mut733.CBAp.cPDE6a | None | ERG | 125 |
| VT: ob | |||||
| FI | |||||
| 12-046 | 42 | AAV2/8mut733.CBAp.cPDE6a | AAV2/8mut733.CBAp.GFP | ERG | 208 |
| VT: ob/cd | |||||
| OCT | |||||
| FI | |||||
| 12-047 | 41 | AAV2/8mut733.CBAp.cPDE6a | AAV2/8mut733.CBAp.GFP | ERG | 208 |
| VT: ob/cd | |||||
| OCT | |||||
| FI | |||||
| 12-048 | 41 | AAV2/8mut733.CBAp.cPDE6a | AAV2/8mut733.CBAp.GFP | ERG | 208 |
| VT: ob/cd | |||||
| OCT | |||||
| FI | |||||
| 12-060 | 44 | AAV2/8mut733.CBAp.cPDE6a | AAV2/8mut733.CBAp.GFP | FI | 58 |
| 12-061 | 44 | AAV2/8mut733.CBAp.cPDE6a | AAV2/8mut733.CBAp.GFP | ERG, FI | 72 |
OD, Right eye; OS, left eye; ERG, electroretinography; VT, vision testing; ob, obstacle course; cd, 4 tunnel choice device; FI, fundus imaging; OCT, optical coherence tomography imaging.