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. 2017 Jun 6;10:2849–2863. doi: 10.2147/OTT.S128810

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© 2017 Chen et al. This work is published and licensed by Dove Medical Press Limited

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Subgroup analysis of OS stratified by tumor types, funnel plot of OS for publication bias, and sensitive analysis of OS.

Notes: (A) High IMP3 expression was significantly associated with poor OS in RCC, lung cancer, oral cancer, urothelial carcinoma, HCC, colorectal cancer, pancreatic cancer, gastric cancer, and ICC but not in ovarian cancer. (B) The funnel plot for OS was asymmetric, which indicated the probability of publication bias. (C) Sensitivity analysis by sequential omission of individual studies did not alter the significance, which confirmed the credibility of outcomes.

Abbreviations: CI, confidence interval; HCC, hepatocellular carcinoma; HR, hazard ratio; ICC, intrahepatic cholangiocarcinoma; In, natural logarithm; IMP3, insulin-like growth factor II mRNA-binding protein 3; OS, overall survival; RCC, renal cell carcinoma; SE, standard error.