Table 5.
Binary logistic regression for risk genotypes predicting cognitive, anxiety, and depression in PD patients.
| B | SE | Wald | df | OR (95%CI) | p | |
|---|---|---|---|---|---|---|
| Cognitive impairment | ||||||
| rs2736990 | ||||||
| CT | 1.355 | 0.703 | 3.714 | 1 | 3.87 (0.97–15.36) | 0.054 |
| CC | 1.346 | 0.705 | 3.641 | 1 | 3.84 (0.96–15.30) | 0.056 |
| Constant | –2.451 | 1.409 | 3.025 | 1 | 0.089 | |
| rs356219 | ||||||
| GA | 1.558 | 0.673 | 5.363 | 1 | 4.74 (1.27–17.75) | 0.021 |
| GG | 1.748 | 0.713 | 6.016 | 1 | 5.74 (1.42–23.21) | 0.014 |
| Constant | –2.668 | 1.407 | 3.598 | 1 | 0.058 | |
| Anxiety | ||||||
| rs2583988 | ||||||
| CT | –0.490 | 0.515 | 0.905 | 1 | 0.61 (0.22–1.68) | 0.341 |
| TT | –1.427 | 0.763 | 3.501 | 1 | 0.24 (0.05–1.07) | 0.061 |
| Constant | 3.364 | 1.474 | 5.212 | 1 | 0.022 | |
| Depression | ||||||
| rs2583988 | ||||||
| CT | 0.106 | 0.540 | 0.039 | 1 | 1.12 (0.38–3.20) | 0.844 |
| TT | –1.520 | 0.762 | 3.983 | 1 | 0.21 (0.04–0.97) | 0.046 |
| Constant | 0.162 | 1.363 | 0.014 | 1 | 0.905 | |
B, regression coefficient; SE, standard error; df, degrees of freedom; OR, odds ratio; CI, confidence interval; p, significance level. Significant p-values are indicated in bold. Only significant and marginally significant associations are shown.