Table 3b.
miRNA | Number of targets identified by target scan | Number of DE gene targets identified by in‐house datasets |
---|---|---|
hsa‐let‐7d‐3p | 479 | 4 |
hsa‐miR‐345‐5p | 3515 | 34 |
hsa‐miR‐423‐5p | 4437 | 41 |
hsa‐miR‐532‐5p | 3227 | 32 |
hsa‐miR‐1296‐5p | 2007 | 13 |
hsa‐miR‐3184‐3p | 3531 | 28 |
hsa‐miR‐423‐3p | 779 | 14 |
hsa‐miR‐199a‐3p | 3013 | 25 |
Differentially expressed (DE) miRs were mapped to TargetScan 7.0. The identified gene targets from TargetScan 7.0 were overlapped to in‐house muscle transcriptome dataset to identify tissue‐specific gene targets for DE miRNA. The identified targets were interrogated for pathway analysis using ingenuity pathway analysis to understand the potential biological roles of the miRNAs in cancer cachexia.