Table 1.
Characteristics of the three cohorts, stratified by age
| MyoAge cohort | Grey Power cohort | Geriatric outpatients | |||
|---|---|---|---|---|---|
| Healthy young | Healthy old | Middle‐aged | Old | ||
| n = 139 | n = 258 | n = 173 | n = 89 | n = 280 | |
| Sociodemographics | |||||
| Age, years, median [IQR] | 22.9 [21.0–25.4] | 73.7 [71.7–77.1] | 62.6 [52.9–66.7] | 74.5 [72.5–78.1] | 82.8 [78.3–87.2] |
| Male, n (%) | 67 (48.2) | 130 (50.4) | 55 (31.8) | 34 (38.2) | 96 (34.3) |
| Independent living, n (%) | 139 (100) | 258 (100) | n/a | n/a | 227 (82.2) |
| Health characteristics | |||||
| Multimorbiditya, n (%) | 0 | 38 (14.7) | 15 (8.7) | 20 (22.5) | 94 (35.5) |
| Polypharmacyb, n (%) | 0 | 22 (8.5) | 4 (2.3) | 10 (11.4) | 151 (56.1) |
| Body composition | |||||
| BMI, kg/m2 | 22.8 (3.0) | 25.4 (3.3) | 25.1 (3.7) | 26.2 (3.8) | 25.9 (4.5) |
| Fat mass, % | 23.1 (9.4) | 30.4 (8.1) | 28.3 (8.5) | 32.5 (8.0) | 30.5 (10.8) |
| Physical performance | |||||
| Gait speed, m/s | 1.85 (0.33) | 1.50 (0.22) | 1.46 (0.20) | 1.39 (0.21) | 0.73 (0.27) |
| Handgrip strength, kg | |||||
| Males | 52.8 (10.0) | 40.4 (7.7) | 48.4 (10.1) | 38.7 (9.5) | 33.5 (6.4) |
| Females | 33.7 (4.9) | 25.9 (5.0) | 31.8 (6.4) | 27.0 (6.1) | 21.0 (4.9) |
| Hand dominance | |||||
| Right‐handed, n (%) | 81 (89.0)c | 159 (97.0)d | 151 (87.3) | 83 (93.3) | 249 (90.5)e |
| Max. HGSdominant f, n (%) | 68 (74.7)c | 131 (79.9)d | 123 (71.1) | 53 (59.6) | 164 (59.6)e |
All values are presented as mean (SD) unless indicated otherwise. IQR, interquartile range, BMI, body mass index; HGS, handgrip strength.
a
Defined as ≥2 diseases including: MyoAge cohort—hypertension, cardiovascular events, noninsulin‐dependent diabetes mellitus, mild chronic obstructive pulmonary disease (COPD), osteoarthritis, arterial surgery and thyroid disease; Grey Power cohort and geriatric outpatients—hypertension, myocardial infarction, stroke, diabetes mellitus, COPD, cancer, Parkinson's disease and rheumatoid arthritis/osteoarthritis.
b
Defined as ≥5 medicaments.
Data available in a subgroup of
c
n = 91,
d
n = 164,
e
n = 275.
f
Maximal HGS reached by the dominant hand.