Figure 1.

(a) Correlation between miR-224 expression level and persistent disease: lower levels of miR-224 were associated with higher risk of persistent (box-and-whisker plot, p = 0.001). (b) Correlation between miR-224 expression level and disease progression: lower levels of miR-224 were associated with higher risk of disease progression (box-and-whisker plot, p = 0.002). (c) miR-224 expression levels and death for disease progression. At the end of the follow-up, patients who died with progressive disease had lower miR-224 levels (box-and-whisker plot, p = 0.0001).