Table 2.
Multivariable Logistic Regression to Predict N Stage (N0–1 vs. N2–3) as Determined by EBUS-TBNA with Interaction Terms for PET-CT
| Parameter Estimate | OR | 95% CI | P Value | ||
|---|---|---|---|---|---|
| Intercept | −1.0663 | 0.21 | |||
| Age, yr | −0.0311 | 0.97 | 0.95 | 0.99 | 0.006 |
| Location | |||||
| Outer two-thirds of lung | 0 | 1.00 | |||
| Central one-third of lung | 0.5881 | 1.80 | 1.07 | 3.03 | 0.03 |
| Histology | |||||
| Adenocarcinoma | 0 | 1.00 | |||
| Squamous cell carcinoma | −0.8235 | 0.44 | 0.26 | 0.731 | 0.002 |
| Non–small cell carcinoma | 0.1423 | 1.15 | 0.55 | 2.43 | 0.71 |
| Other primary lung cancer | −0.5079 | 0.60 | 0.19 | 1.91 | 0.39 |
| N stage by CT and PET | |||||
| CT = N0 or N1, PET = N0 | 0 | 1.00 | |||
| CT = N2 or N3, PET = N0 | 0.9694 | 2.64 | 0.91 | 7.61 | 0.07 |
| CT = N0 or N1, PET = N1 | 1.5766 | 4.84 | 1.83 | 12.8 | 0.002 |
| CT = N2 or N3, PET = N1 | 0.9009 | 2.46 | 0.67 | 9.04 | 0.17 |
| CT = N0 or N1, PET = N2 or N3 | 2.3726 | 10.73 | 4.14 | 27.76 | <0.001 |
| CT = N2 or N3, PET = N2 or N3 | 3.7531 | 42.65 | 18.59 | 97.87 | <0.001 |
Definition of abbreviations: CI = confidence interval; CT = computed tomography; EBUS-TBNA = endobronchial ultrasound–guided transbronchial needle aspiration; OR = odds ratio; PET = positron emission tomography.