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. 2017 Jun 15;195(12):1640–1650. doi: 10.1164/rccm.201607-1408OC

Table 2.

The Top 20 Transcript Clusters Significant at a 1% False Discovery Rate Ordered by Fold Change

Gene Name Avg Expr t Statistic P Value B-H–Adjusted P Value Absolute Fold Change
ORM1 5.56 6.68 2.79 × 10−9 3.61 × 10−6 3.62
DEFA4 6.62 3.69 0.0004 0.0051 3.04
CD177 5.66 4.63 1.39 × 10−5 0.0006 2.52
ARG1 5.09 4.02 0.0001 0.0027 2.29
SLPI 7.69 5.56 3.41 × 10−7 7.05 × 10−5 2.29
MMP9 7.75 4.79 7.42 × 10−6 0.0004 2.28
RNASE3 6.49 4.17 7.61 × 10−5 0.0019 2.26
TXN 7.80 8.80 1.96 × 10−13 2.75 × 10−9 2.22
BCL2A1 6.50 6.03 4.58 × 10−8 2.01 × 10−5 2.19
TNFAIP6 6.85 4.93 4.37 × 10−6 0.0003 2.15
SNORD64 4.68 −4.86 5.57 × 10−6 0.0003 −2.11
ANXA3 7.23 5.38 7.12 × 10−7 0.0001 2.11
CAMP 7.24 4.78 7.82 × 10−6 0.0004 2.11
CSTA 8.41 8.48 8.27 × 10−13 5.81 × 10−9 2.06
HP 5.51 4.11 9.29 × 10−5 0.0021 2.05
CLEC4D 5.87 5.18 1.58 × 10−6 0.0001 2.02
SUB1 7.32 5.37 7.23 × 10−7 0.0001 2.01
OLFM4 4.80 2.88 0.005 0.0301 2.00
PGLYRP1 7.64 5.72 1.71 × 10−7 4.54 × 10−5 1.99
RPL26 8.92 5.64 2.42 × 10−7 5.66 × 10−5 1.97

Definition of abbreviations: Avg Expr = average log2-adjusted expression level for that gene across all the arrays; B-H = Benjamini-Hochberg.

The highest fold change in complete set of differentially expressed genes (n = 1,358) was 3.62.