Table 2.
Baseline Characteristics of Study Subjects
| Allergic Rhinitis (n = 9) | Healthy (n = 8) | P Value | |
|---|---|---|---|
| Age, yr | 28 (25, 37.5) | 35 (25.3, 40) | NS |
| Sex, F/M | 4/5 | 5/3 | NS |
| Baseline FEV1% predicted | 87 (77.5, 94.5) | 106.5 (92, 115) | 0.06 |
| PC20, mg/ml | 0.48 (0.08, 1.5) | >8 | N/A |
| ICS daily dose beclomethasone/equivalent, µg | 400 (250, 650) | 0 | N/A |
| Number of positive skin pricks | 4 (2.5, 5) | 0 | N/A |
| IgE, IU/ml | 196 (76.05, 906) | 23.2* (11.4, 41.3) | 0.005 |
| ACQ | 1.67 (1.3, 2.75) | N/A | N/A |
Definition of abbreviations: ACQ = Asthma Control Questionnaire; ICS = inhaled corticosteroid; N/A = not applicable; NS = nonsignificant; PC20 = concentration of histamine required to reduce FEV1 by 20%.
All atopic patients were skin prick positive to timothy grass, Phleum pratense. Data are displayed as median (25th, 75th percentiles) values, and statistical analysis was carried out using Mann-Whitney U tests.
*
n = 7 healthy subjects.