Table 1.
Subject Demographics and Sputum Culture Data
| Subject | Genotype: G551D/ | Preivacaftor FEV1 [L (% Predicted)] | Sputum Culture Results |
|||
|---|---|---|---|---|---|---|
| Pa | Sa | B | Fungi | |||
| 1 | ΔF508 | 2.80 (79%) | 3+ | |||
| 2 | ΔF508 | 2.42 (72%) | 3+ | 2+ | ||
| 3 | ΔF508 | 2.46 (79%) | 3+ | 1+ | ||
| 4 | ΔF508 | 1.11 (40%) | 3+ | |||
| 5 | ΔF508 | 1.49 (51%) | 3+ | 1+ | ||
| 6 | 3659delC | 1.25 (39%) | 3+ | 2+ | ||
| 7 | ΔF508 | 2.54 (88%) | 3+ | |||
| 8 | P67L | 0.82 (34%) | 1+ | 3+ | ||
| 9 | ΔF508 | 2.16 (77%) | 3+ | 1+ | ||
| 10 | G551D | 3.99 (101%) | 3+ | |||
| 11 | ΔF508 | 1.60 (39%) | 2+ | 3+* | ||
| 12 | R117H | 2.76 (72%) | 3+† | 2+ | ||
Definition of abbreviations: B = Burkholderia; Pa = Pseudomonas aeruginosa; Sa = Staphylococcus aureus.
Fungi (and mold) refers to Candida and Aspergillus. Numeric scoring refers to values assigned by the clinical microbiology laboratory (low = 1+ to high = 3+).
Burkholderia multivorans.
Burkholderia cepacia.