Table 2.
Patients with primary site failure alone at first relapse
| Patient No./Sex | Age at RT (Years) | MYCN Amplified | LDH | Ferritin | Primary Site | Chemo | No. of surgeries to achieve GTR | Time from RT to LF (years) | LF in RT field | Treatment of LF | Current Status |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1/M | 1.5 | Yes | 872 | 448 | L adrenal | N8 | 1 | 0.4 | Yes | Surgery | Deceased |
| 2/F | 3.3 | Yes | 2983 | n/a | L adrenal | ANBL0532 | 1 | 1.1 | Inferior | Surgery, IORT, EBRT | Deceased |
| 3/M | 6.3 | No | 489 | 469 | L adrenal | ANBL0532 | 2 | 1.8 | Yes | Surgery, IORT | Alive, AD |
| 4/F | 5.3 | Yes | n/a | 258 | RP | * | 1 | 0.5 | Yes | Surgery, EBRT | Alive, NED |
| 5/F | 2.6 | Yes | 2000 | 258 | L adrenal | N8 | 2 | 0.4 | Lateral | Surgery, EBRT | Deceased |
| 6/M | 3.2 | Yes | 1511 | 149 | R adrenal | N8 | 1 | 1.0 | Lateral | EBRT | Deceased |
| 7/F | 5.1 | No | 600 | n/a | R adrenal | N8 | 1 | 0.8 | Yes | Surgery, IORT | Deceased |
Abbreviations: No. = number; M = male; F = female; L = left; R = right; GTR = gross total resection; RT = radiation therapy; LF = local failure; RP = retroperitoneal; IORT = intraoperative radiation therapy; EBRT = external beam radiation therapy; AD = active disease; NED = no evidence of disease; n/a = not applicable.
*
Vincristine, cisplatin, cyclophosphamide, doxorubicin in Greece followed by COJEC with carboplatin