Table 5.

Relationship of baseline cognitive factors to likelihood of progression to algorithmic classification of mild cognitive impairment 5 years later (N = 1300)

Algorithm and cognitive factor	AUC	Sensitivity	Specificity
Cognition and CDR
General cognitive performance	0.79	0.74	0.71
Memory	0.77	0.67	0.74
Executive factor	0.70	0.67	0.66
CDR only
General cognitive performance	0.71	0.74	0.61
Memory	0.69	0.62	0.68
Executive factor	0.66	0.67	0.61
Cognition only
General cognitive performance	0.74	0.73	0.62
Memory	0.72	0.68	0.64
Executive factor	0.65	0.57	0.66

Abbreviations: AUC, area under the curve; CDR, Clinical Dementia Rating; ROC, receiving operating characteristic.

NOTE. These ROC analyses show the algorithmic classification based on both cognitive factors and CDR 5 years after baseline and are marginally more associated with baseline cognitive test performance than other algorithmic classifications.