Table 2.

Neuroimaging results

Cluster (voxels)	Region (label)	X	Y	Z	Z statistic
Summary of VBM results
GMMD: MCI > NCI
621	Left hippocampus	−14	−35	2	4.57
		−29	−27	−11	4.27
		−15	−39	5	4.17
		−17	−33	−1	4.07
	Left parahippocampal	−23	−36	−6	3.72
96	Left parahippocampal	−23	7	−23	4.26
		−18	4	−20	4.08
1645	Right hippocampus	38	−24	−7	3.94
		30	−6	−14	3.93
		38	−8	−20	3.85
		27	−32	−3	3.84
		17	−33	3	3.77
	Right parahippocampal cortex	17	−35	−4	3.31
		33	−21	−24	3.25
112	Right parahippocampal cortex	27	11	−23	3.77
Post hoc MLM analysis on the five domains of personality
GMV: interaction with disease: MCI < NCI
209	Left parahippocampal	−24	−22.5	−22.5	3.98
77	Right parahippocampal	24	−27	−19.5	3.91
		24	−31.5	−13.5	3.74
GMMD: interaction with disease: MCI > NCI
905	Right hippocampus	15	−30	−3	4.1
	Right parahippocampal	22.5	−39	−3	4.02
		28.5	−31.5	−13.5	3.78
96	Right parahippocampal	30	10.5	−31.5	4.07
	Right hippocampus	16.5	−31.5	1.5	3.86
		36	−22.5	−9	3.8
		22.5	−31.5	3	3.71
		28.5	−30	−3	3.69
		15	−27	−6	3.5
		13.5	−34.5	6	3.35
90	Right hippocampus	18	−9	−13.5	3.79
154	Right hippocampus	30	−7.5	−12	3.35
		28.5	−6	−21	3.33

Abbreviations: VBM, voxel-based morphometry; GMV, gray matter volume; GMMD, gray matter mean diffusivity; MCI, mild cognitive impairment; MLM, multivariate linear method.