Table 1.
Demographic, clinical and laboratory characteristics of the patient and the control groups according to the SYNTAX score
| Variables | Group 1 (SYNTAX 0-21) (N:25) | Group 2 (SYNTAX ≥22) (N:23) | Controls (N:15) | P |
|---|---|---|---|---|
| Age, years | 58.2±8.12 | 59.1±5.9 | 57.6±9.5 | 0.06 |
| Gender, male % | 52.7 | 53.0 | 52.0 | 0.062 |
| BMI | 24.2±2.1 | 23.8±2.0 | 24.1±1.9 | 0.1 |
| Number of smokers | 16 | 14 | 7 | 0.02 |
| WBC count, 103/mm3 | 8.1±1.15 | 8.1±1.25 | 6.9±1.3 | 0.690 |
| Hb, gr/L | 14.1±0.76 | 13.33±0.83 | 14.36±0.82 | 0.082 |
| Htc | 40.1±2.35 | 38.9±2.35 | 42.93±2.33 | 0.69 |
| Plt count, 103/mm3 | 192±76.2 | 220±84 | 228±84.26 | 0.53 |
| MPV, fL | 7.05±1.05 | 6.55±1.21 | 7.2±1.3 | 0.09 |
| Creatinine, mg/dL | 0.72±0.14 | 0.69±0.17 | 0.69±0.17 | 0.08 |
| AST, U/L | 24±2.15 | 20.16±3.22 | 19.69±3.2 | 0.568 |
| ALT, U/L | 28.2±4.1 | 30.1±5.02 | 26.89±4.12 | 0.784 |
| TG, mg/dL | 169.12±26.1 | 156.88±22.75 | 117.28±22.17 | 0.058 |
| TC, mg/dL | 175.8±19.2 | 188.67±15.95 | 145.62±14.75 | 0.088 |
| LDL, mg/dL | 149.1±12.4 | 153.33±11.83 | 121.92±12.06 | 0.96 |
| Glucose, mg/dL | 115.3±17.09 | 144.3±15.96 | 98.4±8.77 | 0.223 |
| Diabetics, % | 32 | 56.6 | 0 | 0.004 |
| Hypertensives, % | 48 | 43.5 | 0 | 0.051 |
| SBP, mm Hg | 121.22±10.24 | 122.32±11.84 | 113.62±8.23 | 0.258 |
| HR, beat/min | 73.98±12.55 | 72.98±12.55 | 72.23±12.43 | 0.163 |
| EF, % | 60 (55,65) | 57 (54,65) | 65 (52,68) | 0.210 |
| MN frequency, /1000 | 3.8 (1.7,8.2) | 6.2 (1.7,24.5) | 0.83 (0.7,0.9) | 0.001a |
| NDI | 1.43 (1.3,1.7) | 1.42 (1.1,1.8) | 1.54(1.5,1.6) | 0.003b |
| SYNTAX score | 14.2±3.24 | 33.5±1.45 | N/A | 0.001 |
| Gensini score | 55.66±15.32 | 69.7±17.26 | N/A | 0.001 |
| LAD TFC | 14.9±2.6 | 17.9±5.8 | N/A | 0.001 |
| Cx TFC | 12.5±4.2 | 18.3±4.6 | N/A | 0.001 |
| RCA TFC | 9.4±1.1 | 12.3±0.9 | N/A | 0.001 |
Continuous variables were presented as mean ±standard deviation and median (min-max), while categorical variables were given as percentages. The Kolmogorov-Smirnov test was used to verify the normality of the distribution of continuous variables. Statistical analysis of clinical data between two groups consisted of unpaired t-tests for parametric data and Mann-Whitney U test analysis for nonparametric data, whereas one-way analysis of variance or Kruskal-Wallis tests was used to evaluate comparisons between the 3 groups. Post-hoc analysis was carried out by Bonferroni correction test.
ALT - alanine aminotransferase; AST - aspartate aminotransferase; Cx - circumflex artery; EF - ejection fraction; Hb - hemoglobin; HDL - high density lipoprotein; HR - heart rate; Htc - hematocrit; LAD - left anterior descending artery; LDL - low density lipoprotein; MN - micronucleus; MPV - mean platelet volume; NDI - nuclear division index; Plt - platelet; RCA - right coronary artery; SBP - systolic blood pressure; TC - total cholesterol; TG - triglyceride; TFC - thrombolysis in myocardial infarction frame count; WBC - white blood count
Controls and Group 1, P=0.001; Controls and Group 2, P=0.001; Group 1 and Group 2, P=0.001.
Controls and Group 1, P=0.008; Controls and Group 2, P=0.001; Group 1 and Group 2, P=0.002.