Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Jun 19;19:70. doi: 10.1186/s13058-017-0863-0

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Fig. 3 — S100A7 expression knockdown significantly decreased adipose stromal cell (ASC)-derived factors induced proliferation and migration rate in breast carcinoma cells. a S100A7 and receptor for advanced glycation endproducts (RAGE) protein expression levels were significantly reduced by 5 nM small interfering RNA (siRNA) treatment after 72 h. Knockdown of S100A7 expression suppressed adipose stromal cell-derived conditioned medium (ACM) or adipocyte coculture induced (b) proliferation and (c) migration rate in MCF7, SK-BR-3, T47D, and ZR-75-1 cells. siN Negative control small interfering RNA, siS S100A7 small interfering RNA, ctrl Control, Mono Monoculture, +3t3a Coculture with 3T3-L1 adipose stromal cells. * P < 0.05 compared with siN + ACM/3T3a; ** P < 0.0001 compared with control